Relationship between ABO blood type and clinical–pathological characteristics with prostate cancer patients in Khartoum state, Khartoum, Sudan

Wafa Mobarak Ahmed Ali, International university of Africa, faculty of medicine, department of human physiology, Khartoum, Sudan.Follow
Asim Alaaedin Osman, International university of Africa, faculty of medicine, department of human physiology. University of Gadarif, faculty of medicine, department of human physiology, Gadarif, Sudan.Follow
Gad Allah Modawe, Omdurman islamic university, faculty of medicine and health sciences, department of biochemistry, Omdurman, Sudan.Follow

Article Type

Original Study

Abstract

Background: Recent studies have demonstrated the association between ABO blood group and prostate cancer (PC), as well as the various factors associated with PC, including age, family history, ethnicity, and certain viruses. Aim: To demonstrate the association between ABO blood groups and PC and to correlate it with the demographic and clinical features of our studied population. Methods: A descriptive cross-sectional hospital-based study was conducted at the Radiation and Isotopes Center—Khartoum (RICK) in Khartoum state from April 2018 to April 2019. From a study population of 389 PC patients (RICK), a total of 101 were selected. Data was analyzed using SPSS version 21. Results: The mean age of prostate cancer was 66.3 ± 7.8 years; hypertension was the most common chronic disease, affecting 62.3% (63) of patients. Prostate-specific antigen levels increased by more than 10 ng/ml among 74.3% (75) of PC patients. Patients with blood group O had slightly more than one-third, or 37.6% (38), whereas patients with other blood groups had similar percentage ranging from 20% to 22%. No significant relationship was found between ABO blood groups and clinical–pathological characteristics with PC (P-value = 0.067). Conclusion: Our study provides evidence of an association between ABO blood group and clinical–pathological features of PC, hypertension was common in patients with ABO blood group, and there was no significant relationship between ABO blood group and clinical–pathological characteristics of PC.

Keywords

ABO blood group, prostate cancer, clinical pathology, Sudanese

Recommended Citation

Ali, Wafa Mobarak Ahmed; Osman, Asim Alaaedin; and Modawe, Gad Allah (2024) "Relationship between ABO blood type and clinical–pathological characteristics with prostate cancer patients in Khartoum state, Khartoum, Sudan," Iraqi National Journal of Medicine: Vol. 6 : Iss. 1 , Article 4.
Available at: https://doi.org/10.37319/