•  
  •  
 

Article Type

Original Study

Abstract

Background: The idea of convalescent plasma usage is to give passive immunity to the patients, so their immune system has a good chance of combating the virus. This study will review 6 cases of eligible Covid-19 patients that had been treated with convalescent plasma therapy in Basra Covid-19 quarantine._x000D_  _x000D_ Objectives: to demonstrate efficacy and safety of convalescent plasma  in the patient series that had been  enrolled._x000D_  _x000D_ Method:  this study has pioneered a new method to collect up to 3,000 mL of convalescent plasma in one session by an off-label use of Spectra Optia Apheresis systems/TerumoBCT /Exchange set. In this study  250 mL of the collected convalescent plasma had been given to  each of the 6 patients, from one donor. Response in SpO2, dyspnea, and tachypnoea was observed._x000D_ Any reaction to plasma also has been monitored ._x000D_  _x000D_ Result: Our case series have demonstrated both safety and effectiveness of convalescent plasma. This study  was successful in reaching our primary and secondary outcomes in all 6 patients (improvement in SpO2 and symptoms). With negligible difference in time of post transfusion response._x000D_  _x000D_ Conclusion: convalescent plasma is apperantly safe and effective. In this study 250 mL of convalescent plasma has been given to each of the 6 patients, from one donor, using Therapeutic Plasma Exchange (TPE) protocol by Spectra Optia Apheresis system/TerumoBCT. _x000D_  _x000D_

Keywords

convalescent plasma, COVID-19, SARS CoV-2, apheresis, plasma exchange, plasma donation

Creative Commons License

Creative Commons Attribution-NonCommercial 4.0 International License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License

Download

Share

COinS